Q-tube and QianCap are High Pressure reators with Safety Release|Q Labtech

About This Invention

Benefits

Q-TUBE™ is a safe alternative to

A Microwave synthesizer
A Pressure tube / sealed tube
A Dean-Stark Trap
A Parr shaker (hydrogenation)
A CO generator
A Diels-Alder pressure tube

Who is using Q-Tube?

Abilene Christian University
Abbott Labs
Acadia University, Canada
Adamed Sp. z o.o., Poland
Agricultural Univ. of Cracow, Poland
American Radiolabeled Chemicals, Inc.
Amgen
AMRI
Argonne National Laboratory
AstraZeneca
ATK Space Systems
Battelle
Bedoukian Research, Inc.
Bioformix, inc
Biogen Idec
Boehringer Ingelheim
Bridgestone
Bristol-Myers-Squib
DuPont
EMD Serono Research Institute, Inc.
Exelixis
Friedrich-Schiller-Universität Jena
Genentech
GSK
Hoffmann-La Roche AG
Gilead Sciences, Inc.
INVISTA, S.á r.l.
Janssen Pharmaceutica, Belgium
Janssen-Cilag, S.A. , Spain
Johnson & Johnson
Karl-Franzens-University Graz
King Saud university
Lead Discovery Center
Ligand Pharmaceuticals, Inc
Link Technologies Ltd, UK
Merck & Co. inc.
Merck Sharp & Dolme Limited, UK
Miami University
Millennium Pharmaceuticals
Nanyang Technological Univ.,Singapore
NIFG (GNF)
NIH
Nipissing University, Canada
Novartis Institute for Biomedical Research, Inc.
Penn State University
Perkin Elmer
Pfizer
Polyera Corporation
PPD Development
Purdue Pharma LP
Sanofi-Aventis
Sepracor Inc.
Syncom BV
The Dow Chemical Co.
University of California, Berkeley
University of Chicago
University of Hawaii at Hilo
University of Maryland
University of North Dakota
University of Pittsburgh
Unvieristy of Kansas
Vanderbilt University
Ventana Medical Systems
Vertex
Vitae Pharmaceuticals
Wright State University
Xerox Research Ctr. of Canada

A pressure reactor enables a reaction to be carried out at higher

temperature than the boiling point of a solvent and a reagent, which will

increase the reaction rate

(

Arrhenius

Equation:

every 10°C increase

could double the speed). Pressure reduces reaction volume, including

liquid,

which increases concentration and collision frequency, and in turn

speeds

up a reaction. When the desired reaction is accelerated , the

competing reagent decompositions are minimized. Pressure enables

faster reactions

with cleaner profiles.

Q-Tube-12mL

and

35mL

pressure reactors are affordable alternatives to

expensive and cumbersome microwave synthesizers. In addition to organic

synthesis,

Q-TUBE™

and

QianCap™

find use anywhere that higher yields,

cleaner products, and faster reactions are desired, for example in inorganic

synthesis, catalytic hydrogenation, polymerization, acid digestion process

for accurate trace metal analysis, like silver, and other chemical processes.

In addition to the above benefits using the

Q-TUBE™

and

QianCap™

over

a microwave synthesizer,

Q-TUBE™

and

QianCap™

provide extra

advantages of:

Safety-virtually eliminating the risk of pressure explosions
Higher and cleaner product yields (microwave energy is known to

cause

localized

overheat which

accelerates

ecomposition

reactions

especially on

heterocycles)

Scalable (up to 1850 mL)
Higher Pressure than a typical pressure tube
Higher reproducibility (than a microwave)
Greener (broader solvent choices than microwave and conventional
round bottom flask)
Energy savings (92 percent energy reduction and 150 gallons of