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Safe Glass Pressure Q-Tube and QianCap For Your Chemical Research

Regioselective ketone α-alkylation with simple
olefins via dual activation
Fanyang Mo, Prof. Guangbin Dong
Science 4 July 2014, Vol. 345 no. 6192 pp. 68-72
link to the paper

Production of an ​acetone-​butanol-​ethanol mixture
from Clostridium acetobutylicum and its
conversion to high-value biofuels
S Sreekumar, ZC Baer, A Pazhamalai, G Gunbas, A
Pazhamalai, G Gunbas, A Grippo, H Blanch, D S Clark
& F D Toste
Nature Protocols 10, 528–537 (2015)

Bio-based polymer networks by thiol–ene
photopolymerizations of allyl-etherified eugenol
T Yoshimura, T Shimasaki, N Teramoto, M Shibata
European Polymer Journal, Vol 67, June 2015,
Pages 397–408

Highly Selective Condensation of Biomass‐
Derived Methyl Ketones as a Source of Aviation
ER Sacia, M Balakrishnan, MH Deaner, KA Goulas,
Prof. F. D Toste and Prof. A. T. Bell
ChemSusChem, Vol. 8, Issue 10, pages 1726–1736,
May 22, 2015

Concise synthesis of 12a-methyl-11-aryl-1, 2-
dihydrobenzo [f] pyrrolo [1, 2-a] quinolin-3 (12aH)-
ones as racemic 14-azaestrogen analogs
AM Abdelkhalik, NK Paul, A Jha
Steroids, Vol. 98, June 2015, Pages 107–113

Synthesis and characterization of mackinawite
nanocrystals (FeSm) and their application in
recovery of aqueous Hg (II) solution
SM Alshehri, A Aldalbahi, T Ahamad, N Alhokbany
Desalination and Water Treatment
Vol. 55, Issue 12, 2015

Compositions and kits for diagnosing infections
G Timmins, T Wu, SW Choi
US Patent App. 14/596,926, 2015

E Altmann, U Hommel, ELJ Lorthiois
US Patent App. 14/409,911, 2015

Novel pathways for fuels and lubricants from
biomass optimized using life-cycle greenhouse
gas assessment
M Balakrishnan, E Sacia, S Sreekumara, G Gunbasa, A
Gokhalea, C Scowna, F. D Toste and A. T. Bell
PNAS, June 23, 2015, vol. 112 no. 25

Upgrading Lignocellulosic Products to Drop‐In
Biofuels via Dehydrogenative Cross‐Coupling and
Hydrodeoxygenation Sequence
S Sreekumar, M Balakrishnan, K Goulas, G Gunbas, A.
Gokhale, L Louie, A Grippo, C Scown, Prof. A T. Bell,
Prof.  F. D Toste
ChemSusChem, Vol. 8, Issue 16, pages 2609–2614,
August 24, 2015

The twin drug approach for novel nicotinic
acetylcholine receptor ligands
Isabelle Tomassoli, Daniela Gündisch
Bioorganic & Medicinal Chemistry
Vol. 23, Issue 15, 1 August 2015, Pages 4375–4389

A New Route to the Versatile Synthesis of
Thiopyrano [2, 3-b: 6, 5-b'] diindoles via 2-
M Jha, M Edmunds, K Lund, A Ryan
Tetrahedron Letters, Volume 55, Issue 41, 8 October
2014, Pages 5691–5694

Chemocatalytic Upgrading of Tailored
Fermentation Products Toward Biodiesel
Dr. S.Sreekumar, Z.C.Baer, Dr. E.Gross, Dr. S.
Padmanaban, K.Goulas, G.Gunbas, Dr. S Alayoglu,
Prof. Harvey W. Blanch, Prof. Douglas S. Clark and
Prof. F. Dean Toste
ChemSusChem 15 July 2014, Vol. 7, Issue 9

High-performance bio-based thermosetting resins
based on bismaleimide and allyl-etherified
eugenol derivatives
M Neda, K Okinaga, M Shibata
Materials Chemistry and Physics, Volume 148,
Issues 1–2, 14 November 2014, Pages 319–327

Engineering Clostridium acetobutylicum for
production of kerosene and diesel blendstock
S.Bormanna, Z.C.Baer, S.Sreekumar, J.M.
Kuchenreuthera, F.Dean Toste, Harvey W. Blanch,
Douglas S. Clark
Metabolic Engineering, Volume 25, September 2014,
Pages 124–130

Non-Conventional Methodologies in the Synthesis
of 1-Indanones
M.Oliverio, M.Nardi, P.Costanzo, L.Cariati, G.Cravotto,
S.V.Giofrè and A.Procopio
Molecules 2014, 19, 5599-5610

Facile Ecofriendly Synthesis of Monastrol and Its
Structural Isomers via Biginelli Reaction
M.Oliverio, P.Costanzo, M.Nardi, I.Rivalta, and A.
ACS Sustainable Chemistry & Engineering, 2014

"Discovery of Dap-3 Polymyxin Analogs for the
Treatment of Multidrug-Resistant Gram-negative
Nosocomial Infections"
Thomas V. Magee, Matthew F. Brown, Jeremy T. Starr,
et al.
J. Med. Chem. 2013, 56, 5079−5093

"Syntheses and evaluation of macrocyclic
engelhardione analogs as antitubercular and
antibacterial agents"
Dianqing Sun, et al. The Journal of Antibiotics (2013)
66, 319–325

"Bronsted acid-catalyzed rapid enol-ether
formation of 2-hydroxyindole-3-carboxaldehydes"
D. Blanchard, TS Cameron, M. Jha - Molecular
17: 827-834, 2013 - Springer

"Palladium-Catalysed Dehydrogenative
Generation of Imines from Amines. A Nature-
Inspired Route to Indoles via Cross-Couplings of
Amines with Arylhydrazines"
Maurizio Taddei, Manuel G. Mura, Suvi Rajamäki.
Advanced Synthesis & Catalysis, Vol. 355, Issue 14-
15, pages 3002–3013, October 11, 2013

"Bio-based thermosetting bismaleimide resins
using eugenol, bieugenol and eugenol novolac"
Mitsuhiro Shibata, Naozumi Tetramoto, Ayumi Imada.
Reactive and Functional Polymers,
Vol. 73, Issue 8,
August 2013, Pages 1086–1095
About Us

Q Labtech is a U.S.-based laboratory technology company.
Our patented technology features a pressure-release and
reseal system that prevents accidental explosions due to
over pressurization in the pressure reactor. Our products,
Q-Tube (pressure reactor) and QianCap (safety cap for
Ace type pressure bottles), are affordable alternatives to
microwave synthesizers. Our Fisher-Porter type of purging
systems can be used for hydrogenation and gas-filled
pressurized reactions.  

How Does Pressure Impact Chemical Reactions?

A pressure reactor enables a reaction to be carried out at
higher temperature than the boiling point of a solvent and
a reagent, which will increase the reaction rate (Arrhenius
Equation: every 10°C increase could double the speed).
Pressure reduces reaction volume, including liquid, which
increases concentration and collision frequency, and in
turn speeds up a reaction. When the desired reaction is
accelerated , the competing reagent decompositions are
minimized. Pressure enables faster reactions with cleaner

The Benefits of Our Products

Q-Tube™ and QianCap™ PURGING systems can be
operated safely and accurately with high reproducibility
with a wide range of gases, including Ammonia, Nitrogen,
Argon, Hydrogen, Deuterium, Carbon Monoxide, Carbon
Dioxide, etc.

Q-Parallel Synthesizer™ enable multiple simultaneous
reactions to be done in about 40 minutes; a great tool for
reaction optimization and pressurized parallel synthesis.

Q-Tube-12mL and 35mL pressure reactors are affordable
alternatives to expensive and cumbersome microwave
synthesizers. In addition to organic synthesis, Q-Tube™  
and QianCap™ find use anywhere that higher yields,
cleaner products, and synthesis, catalytic hydrogenation,
polymerization, acid digestion process for accurate trace
metal analysis, like silver, and other chemical processes.

In addition to the above benefits using the Q-TUBE™ and
QianCap™ overa microwave synthesizer, Q-TUBE™ and
QianCap™ provide extra advantages of:

  • Safety-virtually eliminating the risk of pressure
  • Higher and cleaner product yields (microwave
    energy is known to cause localized overheat which
    accelerates decomposition reactions especially on
  • Scalable (up to 1850 mL)
  • Higher Pressure than a typical pressure tube
  • Higher reproducibility (than a microwave)
  • Greener (broader solvent choices than microwave
    and conventional round bottom flask)
  • Energy savings (92 percent energy reduction and
    150 gallons of water per refluxed reaction)
  • Affordable, only a fraction of a microwave synthesizer
  • Maintenance-free
More Publications

"Efficient synthesis of ionic liquids/precursors using
a Q-Tube (TM)."
Krol, M. Joseph, Andrew Beauchamp, and William A. Feld.
Vol. 245. 1155 16TH ST, NW, WASHINGTON,

"Inhibitors of influenza viruses replication"
Paul S. Charifson, Michael P. Clark, et al.
US 20130345218 A1

"Rollover Cyclometalation Pathway in Rhodium
Catalysis: Dramatic NHC Effects in the C−H Bond
Jaesung Kwak, Youhwa Ohk, Yousung Jung, and Sukbok
, J. Am. Chem. Soc. 2012, 134, 17778−17788

"Synthesis, Evaluation, and Radiolabeling of New
Potent Positive Allosteric Modulators of the
Metabotropic Glutamate Receptor 2 as Potential
Tracers for Positron Emission Tomography Imaging"
José-Ignacio Andrés, Jesús Alcázar, JoséMaría Cid.
J. Med. Chem.
2012, 55, 8685−8699

"Polymyxin Derivates Useful As Antibacterial Agents"
Magee, Thomas Victor, et al. U.S. Patent No.
13 Dec. 2012.

"Imidazo[5,1-f][1,2,4]Triazines for the Treatment of
Neurological Disorders"
homas A. Chappie, Christopher J. Helal, John M.
U.S.  20120214791 A1

"Molecular Vibration-Sensing Component in Human
Gane S, Georganakis D, Maniati K, Vamvakias M,
Ragoussis N, et al.
(2013) PLoS ONE 8(1): e55780.

"Diels-Alder Reactions of Dienophiles and
Cyclopentadiene Using a Sealed Tube Protocol"
Richard T. Taylor*, Christopher M. Goins and Katherine R.
Miami University

"Preparation and characterization of rhenium(I)
dicarbonyl complexes based on the meridionally-
coordinated terpyridine ligand."      
Daniel R. Black, Sean E. Hightower. Inorganic Chemistry
Vol. 24, October 2012, Pages 16–19

"Synthesis of CdS Nanocrystals Using Polymer Metal
Complex as a Single Source Precursor and their
Physicochemical Properties."  
Ahamad, Tansir, and Saad M. Alshehri. Nano Hybrids 1
(2012): 45-56.

"Double Schiff Base Adducts of 2,3-Butanedione with
Glycine: Formation of Pyrazine Rings with the
Participation of Amino Acid Carbon Atoms."
Paula Vanessa Guerra and Varoujan A. Yaylayan. J. Agric.
Food Chem.,
2012, 60 (45), pp 11440–11445

"Role of the Ribose-Specific Marker Furfuryl-amine in
the Formation of Aroma Active 1-(Furan-2-ylmethyl)-1
H-pyrrole (or Furfuryl-
pyrrole Derivatives."                            
Plamen Y. Nikolov and Varoujan A. Yaylayan. J.
Food Chem., 2012, 60 (40), pp 10155–10161

"Synthesis and Structure-Activity Relationships of
Lansine Analogues as Antileishmanial Agents."
Pieroni, Marco, et al. ChemMedChem (Vol.7, 1895-1900,